Prof. Dr.-Ing. Stefan Glasauer

Senior Scientist
Center for Sensorimotor Research 
Department of Neurology
Bernstein Center for Computational Neuroscience
German Vertigo Center DSGZ

Ludwig-Maximilians-Universität München
Klinikum der Universität München, Neurological Research Center 
Feodor-Lynen-Straße 19, 81377 Munich, Germany 

Tel: (49) 89/44007 4839 Fax (49) 89/44007 4801 
sglasauer (at) lmu.de

Lectures
Group

Postdocs

Alicia Costalago Meruelo

PhD Students

Dian Anggraini* Nisha Dalal Isabelle Garzorz Kathrin Kostorz
Alexander Knorr
Mehrdad Salmasi Joshua Yudice

Diploma/
Bachelor/Master



Other Members

Ulrich Büttner

Students



Previous members

PostDocs: Lukas Brostek, Paul Maier, Yi-Huang Su, Murat Saglam, Virginia Flanagin, Alexandra Stein, W. Geoffrey Wright, Nadine Lehnen, Olympia Kremmyda, Ulrich Nuding, Miruna Szabo, Christian Rössert

PhD students: Johanna Schuller*, Rainer Bögle*, Markus Huber, Aleksandra Kupferberg, Frederike Petzschner, Lukas Brostek, Eva Fraedrich, Magdalena Wutte, Patrizia Basili, Bert Karcher, Sandra Pfanzelt*, Anna Dresel (geb. Günther), Andreas Wilden*

Undergraduates: Johanna Bayer, Ariane Böhm, Nicola Palandt, Julia Rackerseder, Maria Herrerra, Anna Kasparbauer, Christopher Roppelt, Bartosz Helfer, Julia Kärcher, Ben Krebs, Gil Sharvit, Erich Schneider

Main Research Topics

Perception of spatial orientation and the role of the vestibular system: theory and experiments 
Human path integration during active and passive motion 
Ocular motor system: experimental analysis and mathematical modelling 
Influence of vision and eye movements on postural stability 
Human vestibular perception (rotating chairs, driving simulators) 
Processing of vestibular information in the brainstem and the cerebellum 
Mechanisms of spatial working memory
Human-human and human-robot joint interaction 
Colour perception

Further Information: Neurological Research Center or BCCN

Selected Literature

The Colour Book

Steinbrenner J, Glasauer S (eds.): Farben. Betrachtungen aus Philosophie und Neurowissenschaften. Frankfurt, Suhrkamp Taschenbuch Wissenschaft, 2007

Stefan Glasauer on ResearchGate

A more complete list of papers at PubMed

Selected older papers:

Perception of spatial orientation and navigation

  • Petzschner F, Glasauer S. Iterative Bayesian estimation as an explanation for range and regression effects: A study on human path integration. J Neurosci 31:17220-9, 2011
  • Glasauer S, Stein A, Günther AL, Flanagin VL, Jahn K, Brandt T: The effect of dual tasks in locomotor path integration. Ann NY Acad Sci 1164: 201–205, 2009
  • Brandt T, Glasauer S, Strupp M, Dieterich D. Spatial neglect: hypothetical mechanisms of disturbed interhemispheric crosstalk for orientation. Ann NY Acad Sci 1164: 216–221, 2009
  • Günther AL, Bartl K, Nauderer J, Schneider E, Huesmann A, Brandt T, Glasauer S. Modality-dependent indication of the subjective vertical during combined linear and rotational movements. Ann NY Acad Sci 1164: 376–379, 2009
  • Schneider E, Bartl K, Glasauer S. Galvanic vestibular stimulation combines with earth-horizontal rotation in roll to induce the illusion of translation. Ann NY Acad Sci 1164: 116–118, 2009
  • Kupferberg A, Glasauer S, Stein A, Brandt T. Influence of uninformative visual cues on gravity perception. Ann NY Acad Sci 1164: 403–405, 2009
  • Wright WG, Schneider E, Glasauer S. Compensatory manual motor responses while object wielding during combined linear visual and physical roll tilt stimulation. Exp Brain Res 192:683-694, 2009
  • Seemungal B, Glasauer S, Gresty M, Bronstein A. Vestibular perception and navigation in the congenitally blind. J Neurophysiol 97: 4341-4356, 2007
  • Glasauer S, Schneider E, Grasso R, Ivanenko YP. Space-time relativity in self-motion reproduction. J Neurophysiol 97: 451-461, 2007 PDF
  • Glasauer S Brandt T. Non-commutative updating of perceived self-orientation in three dimensions. J Neurophysiol. 97: 2958-2964, 2007
  • Wright WG, Glasauer S. Subjective somatosensory vertical during dynamic tilt is dependent on task, inertial condition, and multisensory concordance. Exp Brain Res 172:310-21. 2006
  • Wright WG, Glasauer S: Haptic Subjective Vertical Shows Context Dependence: Task and Vision Play a Role during Dynamic Tilt Stimulation. Ann NY Acad Sci 1004: 531-533, 2003
  • Glasauer S, Amorim MA, Viaud-Delmon I, Berthoz A. Differential effects of labyrinthine dysfunction on distance and direction during blindfolded walking of a triangular path. Exp Brain Res 145, 489-497, 2002

Brain imaging studies (perception, navigation, etc.)

  • Fraedrich E, Flanagin F, Duann JR, Brandt T, Glasauer S. Hippocampal involvement in processing of indistinct visual motion stimuli. J Cogn Neurosci 24:1344-57, 2012
  • Wutte MG, Glasauer S, Jahn K, Flanagin VL. Moving and being moved: Differences in cerebral activation during recollection of whole-body motion. Behav Brain Res. 227:21-9, 2012
  • Hüfner K, Binetti C, Hamilton DA, Stephan T, Flanagin VL, Linn J, Labudda K, Markowitsch H, Glasauer S, Jahn K, Strupp M, Brandt T. Structural and functional plasticity of the hippocampal formation in professional dancers and slackliners. Hippocampus 21:855-65, 2011
  • Fraedrich EM, Glasauer S, Flanagin VL. Spatiotemporal phase-scrambling increases visual cortex activity. Neuroreport 21:596-600, 2010
  • Flanagin VL, Wutte M, Glasauer S, Jahn K. Driving dreams: cortical activations during imagined passive and active whole body movement. Ann NY Acad Sci 1164: 372–375, 2009
  • Deutschländer A, Hüfner K, Kalla R, Stephan T, Dera T, Glasauer S, Wiesmann M, Strupp M, Brandt T. Unilateral vestibular failure suppresses cortical visual motion processing. Brain 131: 1025-1034, 2008
  • Hüfner K, Kalla R, Hamilton DA, Stephan T, Glasauer S, Ma J, Brüning R, Markowitsch HJ, Labudda K Schichor C, Strupp M, Brandt T. Spatial memory and hippocampal volume in humans with unilateral vestibular deafferentation. Hippocampus 17:471-485, 2007
  • Brandt T, Glasauer S, Stephan T, Bense S, Yousry TA, Deutschländer A, Dieterich M: Visual-vestibular and visuo-visual cortical interaction: New Insights from fMRI and PET. Ann NY Acad Sci 956: 230-241, 2002

Computational modelling of eye (and head) movements

  • Brostek L, Büttner U, Mustari MJ, Glasauer S. Neuronal Variability of MSTd Neurons Changes Differentially With Eye Movement and Visually Related Variables. Cereb Cortex. 2012
  • Saglam M, Lehnen N, Glasauer S. Optimal control of natural eye-head movements minimizes the impact of noise. J Neurosci 31:16185-93, 2011
  • Glasauer S, Rössert C, Strupp M. The role of regularity and synchrony of cerebellar Purkinje cells for pathological nystagmus. Ann N Y Acad Sci 1233:162-7, 2011
  • Rössert C, Moore L, Straka H, Glasauer S. Cellular and network contributions to vestibular signal processing: impact of ion conductances, synaptic inhibition and noise. J Neurosci 31:8359-72, 2011 PDF
  • Brostek L, Eggert T, Ono S, Mustari MJ, Büttner U, Glasauer S. An information-theoretic approach for evaluating probabilistic tuning functions of single neurons. Front Comput Neurosci 5:15, 2011 PDF
  • Rössert C, Straka H, Glasauer S, Moore LE. Frequency-domain analysis of intrinsic neuronal properties using high-resistant electrodes. Front Neurosci 3:64, 2009 PDF
  • Rössert C, Pfanzelt S, Straka H, Glasauer S. Modeling of intrinsic and synaptic properties to reveal the cellular and network contribution for vestibular signal processing. Ann NY Acad Sci 1164: 451–454, 2009
  • Glasauer S, Rössert C. Modelling drug modulation of nystagmus. Prog Brain Res 171:527-534, 2008
  • Nuding U, Ono S, Mustari M, Büttner U, Glasauer S. A theory of the dual pathways for smooth pursuit based on dynamic gain control. J Neurophysiol 99:2798-2808, 2008
  • Marti S, Straumann D, Büttner U, Glasauer S. A model-based theory on the origin of downbeat nystagmus. Exp Brain Res 188:613-631, 2008
  • Günthner W, Glasauer S, Wagner P, Ulbrich H. Biomimetic Control for Adaptive Camera Stabilization in Driver-Assistance Systems. J Mech Sci Technol 21:930-934, 2007
  • Marti S, Straumann D, Glasauer S: The origin of downbeat nystagmus: an asymmetry in the distribution of on-directions of vertical gaze-velocity Purkinje cells. Ann NY Acad Sci 1039: 548-553, 2005
  • Glasauer S: Cerebellar contribution to saccades and gaze holding: a modelling approach. Ann NY Acad Sci 1004: 206-219, 2003
  • Schneider E, Glasauer S, Brandt T, Dieterich M: Nonlinear Nystagmus Processing Causes Torsional VOR Nonlinearity. Ann NY Acad Sci 1004:500-505, 2003
  • Glasauer S, Dieterich M, Brandt T: Central positional nystagmus simulated by a mathematical ocular motor model of otolith-dependent modification of Listing’s plane. J Neurophysiol 86: 1546-1554, 2001
  • Glasauer S, Dieterich M, Brandt T: Modeling the role of the interstitial nucleus of Cajal in otolithic control of static eye position. Acta Otolaryngol Suppl. 545: 105-107, 2001

Functional magnetic resonance imaging of eye movements

  • Hüfner K, Stephan T, Flanagin VL, Deutschländer A, Dera T, Karch C, Linn J, Glasauer S, Dieterich M, Strupp M, Brandt T .Cerebellar and visual gray matter brain volume increases in congenital nystagmus. Front Neurol 2:60, 2011 PDF
  • Glasauer S, Stephan T, Kalla R, Marti S, Straumann D. Up-Down Asymmetry of Cerebellar Activation During Vertical Pursuit Eye Movements. Cerebellum 8:385-8, 2009
  • Hüfner K, Stephan T, Glasauer S, Kalla R, Riedel E, Deutschländer A, Dera T, Wiesmann M, Strupp M, Brandt T. Differences in saccade-evoked brain activation patterns with eyes open or eyes closed in complete darkness. Exp Brain Res 186:419-430, 2008
  • Hüfner K, Stephan T, Kalla R, Deutschländer A, Wagner J, Holtmannspötter M, Schulte-Altedorneburg G, Wiesmann M, Strupp M, Brandt T, Glasauer S. Structural and functional MRIs disclose cerebellar pathologies in idiopathic downbeat nystagmus. Neurology 69:1128-1135, 2007
  • Kalla R, Deutschländer A, Hüfner K, Stephan T, Jahn K, Glasauer S, Brandt T, Strupp M. Detection of floccular hypometabolism in downbeat nystagmus by fMRI. Neurology 66: 281-283, 2006

Experimental analysis of eye (and head) movements

  • Spiegel R, Kalla R, Rettinger N, Schneider E, Straumann D, Marti S, Glasauer S, Brandt T, Strupp M. Head position during resting modifies spontaneous daytime decrease of downbeat nystagmus. Neurology 75:1928-1932, 2010
  • Ono S, Brostek L, Nuding U, Glasauer S, Büttner U, Mustari MJ. The response of MSTd neurons to perturbations in target motion during ongoing smooth pursuit eye movements. J Neurophysiol 103:519-530, 2010 PDF
  • Kremmyda O, Rettinger N, Strupp M, Büttner U, Glasauer S. Teaching video neuroimages: unilateral RIMLF lesion: pathologic eye movement torsion indicates lesion side and site. Neurology 73(18):e92-3, 2009
  • Spiegel R, Rettinger N, Kalla R, Lehnen N, Straumann D, Brandt T, Glasauer S, Strupp M. The intensity of downbeat nystagmus during daytime. Ann NY Acad Sci 1164: 293–299, 2009
  • Lehnen N, Büttner U, Glasauer S. Vestibular guidance of active head movements. Exp Brain Res 194:495-503, 2009
  • Nuding U, Kalla R, Muggleton NG, Büttner U, Walsh V, Glasauer S. TMS evidence for smooth pursuit gain control by the frontal eye fields. Cereb Cortex 19:1144-50, 2009
  • Pfanzelt S, Rössert C, Rohregger M, Glasauer S, Moore LE, Straka H. Differential dynamic processing of afferent signals in frog tonic and phasic second-order vestibular neurons. J Neurosci 28:10349-62, 2008
  • Bayer O, Eggert T, Glasauer S, Büttner U. Human smooth pursuit gain is modulated by a signal related to gaze velocity. NeuroReport 19:1217-1220, 2008
  • Kalla R, Glasauer S, Büttner U, Brandt T, Strupp M. 4-Aminopyridine Restores Vertical and Horizontal Neural Integrator Function in Downbeat Nystagmus. Brain 130:2441-2451, 2007
  • Zingler VC, Denecke K, Jahn K, von Meyer L, Krafczyk S, Krams M, Elfont R, Brandt T, Strupp M, Glasauer S. The effect of nicotine on perceptual, ocular motor, postural, and vegetative functions at rest and in motion. J Neurol 254:1689–1697, 2007
  • Ladda J, Eggert T, Glasauer S, Straube A. Velocity scaling of cue-induced smooth pursuit acceleration obeys constraints of biological motion. Exp Brain Res 182:343-56, 2007
  • Kremmyda O, Büttner-Ennever JA, Büttner U, Glasauer S. Torsional deviations with voluntary saccades due to a unilateral midbrain lesion. J Neurol Neurosurg Psychiatry 78:1155-1157, 2007
  • Zingler VC, Kryvoshey D, Schneider E, Glasauer S, Brandt T, Strupp M. A clinical test of otolith function: static ocular counterroll with passive head tilt. Neuroreport 17:611-615, 2006
  • Brandt T, Glasauer S, Schneider E. A third eye for the surgeon. J Neurol Neurosurg Psychiatry 77: 278, 2006 PDF
  • Bartl K, Schneider E, Glasauer S. Dependence of the torsional vestibulo-ocular reflex on the direction of gravity. Ann N Y Acad Sci. 1039:455-458, 2005
  • Glasauer S, Hoshi M, Büttner U: Smooth pursuit in patients with downbeat nystagmus. Ann NY Acad Sci 1039: 532-535, 2005
  • Glasauer S, Kalla R, Büttner U, Strupp M, Brandt T. 4-aminopyridine restores visual ocular-motor function in upbeat nystagmus. J Neurol Neurosurg Psychiatry 76:451-453, 2005 PDF
  • Schneider E, Glasauer S, Dieterich M, Kalla R, Brandt T: Diagnosis of Vestibular Imbalance in the Blink of an Eye. Neurology 63:1209-1216, 2004
  • Glasauer S, von Lindeiner H, Siebold S, Büttner U: Vertical vestibular responses to head impulses are symmetrical in downbeat nystagmus. Neurology 63: 621-625, 2004
  • Glasauer S, Hoshi M, Kempermann U, Eggert T, Büttner U. Three-dimensional eye position and slow phase velocity in humans with downbeat nystagmus. J. Neurophysiol. 89: 338-354, 2003 PDF
  • Schneider E, Glasauer S, Dieterich M: A comparison of human ocular torsion patterns during natural and galvanic vestibular stimulation. J Neurophysiol 87:2064-2073, 2002
  • Schneider E, Glasauer S, Dieterich M: Central processing of human ocular torsion analyzed by galvanic vestibular stimulation. NeuroReport 11:1559-1563, 2000

Human-human and human-robot joint interaction

  • Kupferberg A, Huber M, Helfer B, Lenz C, Knoll A, Glasauer S. Moving just like you: motor interference depends on similar motility of agent and observer. PLoS One 7(6):e39637, 2012
  • Burkart J, Kupferberg A, Glasauer S, van Schaik C.Even simple forms of social learning rely on intention attribution in marmoset monkeys (Callithrix jacchus). J Comp Psychol 126:129-38, 2012
  • Kupferberg A, Glasauer S, Huber M, Rickert M, Knoll A, Brandt T. Biological movement velocity profile increases acceptance of humanoid robots as human partners in motor interaction. AI & Society 26, 2011
  • Glasauer S., Huber M., Basili P., Knoll A., and Brandt T. Interacting in time and space: Investigating human-human and human-robot joint action. Proc 19th IEEE Int Symp on Robot and Human Interactive Communication, pp. 252 - 257, 2010
  • Kirsch A, Kruse T, Sisbot EA, Alami R, Lawitzky M, Bršcic D, Hirche S, Basili P, Glasauer S. Plan-Based Control of Joint Human-Robot Activities. Künstl Intell 24: 223–231, 2010
  • Kupferberg A, Glasauer S, Huber M, Rickert M, Knoll A, Brandt T. Video observation of humanoid robot movements elicits motor interference. In: Proceedings New Frontiers in Human-Robot Interaction (Dautenhahn K, Ed.), SSAISB: The Society for the Study of Artificial Intelligence and the Simulation of Behaviour ISBN - 190295680X, Edinburgh 2009, pp 81-85
  • Huber M, Knoll A, Brandt T, Glasauer S. Handing over a cube: spatial features of physical joint-action. Ann NY Acad Sci 1164: 380–382, 2009
  • Huber M, Rickert M, Brandt T, Knoll A, Glasauer S. Human-robot interaction in handing-over tasks. Proc 17th IEEE Int Symp Robot Human Interactive Communication, pp. 107-112, 2008

Posture and eye movements

  • Glasauer S, Schneider E, Jahn K, Strupp M, Brandt T. How the eyes move the body. Neurology 65: 1291-1293, 2005
  • Strupp M, Glasauer S, Jahn K, Schneider E, Krafczyk S, Brandt T: Eye Movements and Balance. Ann NY Acad Sci 1004: 352-358, 2003
  • Jahn K, Strupp M, Krafczyk S, Schüler O, Glasauer S, Brandt T. Suppression of eye movements improves balance. Brain 125: 2005-2011, 2002 PDF

Canal-otolith interaction in a deep cerebellar nucleus (project finished)

  • Büttner U, Glasauer S, Glonti L, Guan Y, Kipiani E, Kleine JF, Siebold C, Wilden A: Multimodal signal integration in vestibular neurons of the primate fastigial nucleus. Ann NY Acad Sci 1004: 241-251, 2003
  • Wilden A, Glasauer S, Kleine JF, Büttner U: Modelling transfer characteristics of vestibular neurons in the fastigial nucleus of the behaving monkey on the basis of canal-otolith interaction. Neuroreport 13: 799-804, 2002
  • Siebold C, Anagnostou E, Glasauer S, Glonti L, Kleine J, Tchelidze T, Büttner U: Canal-otolith interaction in the fastigial nucleus of the alert monkey. Exp Brain Res 136: 169-178, 2001
 

Grip force control (project finished)

  • Nowak D, Hermsdörfer J, Schneider E, Glasauer S: Moving objects in a rotating environment: Rapid prediction of Coriolis and centrifugal force perturbations. Exp Brain Res 157:241-254, 2004
  • Nowak D, Glasauer S, Hermsdörfer J: How predictive is grip force control in the complete absence of somatosensory feedback? Brain 127:182-192, 2003 PDF
  • Nowak D, Glasauer S, Hermsdörfer J: Grip force efficiency in long-term deprivation of somatosensory feedback. NeuroReport 14:1803-1807, 2003
  • Nowak D, Glasauer S, Meyer L, Mai N, Hermsdörfer J: The role of cutaneous feedback for anticipatory grip force adjustments during object movements and externally imposed variation of the direction of gravity. Somatosens Mot Res 19: 49-60, 2002
  • Nowak D, Hermsdörfer J, Glasauer S, Phillip J, Meyer L, Mai N: The effects of digital anesthesia on predictive grip force adjustments during vertical movement of a grasped object. Europ J Neurosci 14: 756-762, 2001
  • Hermsdörfer J, Marquardt C, Phillip J, Zierdt A, Nowak D, Glasauer S, Mai N: Moving weightless objects: grip force control during microgravity. Exp Brain Res 132: 52-64, 2000

Selected older papers on the perception of spatial orientation and locomotion for download:

  • Mittelstaedt ML, Glasauer S: Idiothetic navigation in gerbils and humans. Zool Jb Physiol 95:427-435. 1991 PDF
  • Glasauer S: Interaction of semicircular canals and otoliths in the processing structure of the subjective zenith. Ann. NY Acad. Sci. 656: 847-849. 1992 PDF
  • Glasauer S, Mittelstaedt H: Determinants of orientation in microgravity. Acta Astronautica 27:1-9. 1992 PDF
  • Glasauer S: Human spatial orientation during centrifuge experiments : Non-linear interaction of semicircular canals and otoliths. In: Proceedings of the XVIIth Barany Society Meeting (Krejcova H, Jerabek J, eds.) Prague. 48-52. 1993 PDF
  • Mittelstaedt ML, Glasauer S: The contribution of inertial and substratal information to the perception of linear displacement. In: Proceedings of the XVIIth Barany Society Meeting (Krejcova H, Jerabek J, eds.) Prague. 102-105. 1993 PDF
  • Glasauer S, Amorim MA, Vitte E, Berthoz A. Goal directed linear locomotion in normal and labyrinthine-defective subjects. Exp Brain Res 98:323-335, 1994 PDF
  • Glasauer S, Amorim MA, Bloomberg JJ, Reschke MF, Peters BT, Smith SL, Berthoz A: Spatial orientation during locomotion following space flight. Acta Astronautica 36:423-431, 1995 PDF
  • Glasauer S: Linear acceleration perception : frequency dependence of the hilltop illusion. Acta Otolaryngol Suppl 520, 37-40, 1995 PDF
  • Glasauer S, Merfeld DM: Modeling three dimensional vestibular responses during complex motion stimulation. In: Three-Dimensional Kinematic Principles of Eye-, Head-, and Limb Movements in Health and Disease (Fetter M, Haslwanter T, Misslisch H, Tweed D, eds.) Harwood Amsterdam 1997, pp 387-398 PDF
  • Glasauer S, Mittelstaedt H: Perception of spatial orientation in different g-levels. Journal of Gravitational Physiology 4(2):P5-P8, 1998  PDF

Part of my PhD thesis on the dynamics of the Subjective Visual Vertical

  • Glasauer S: Das Zusammenspiel von Otolithen und Bogengängen im Wirkungsgefüge der Subjektiven Vertikale. PhD thesis, Technical University Munich, 1991. PDF

Methods

  • Mathematical modeling and simulation
  • Psychophysics of spatial orientation, navigation, and motion perception using various stimulation devices (virtual reality, rotating chair, human centrifuge, sled and robot, driving simulator, microgravity: space flight and parabolic flight)
  • Eye movement recordings by various methods (dual search-coil, video-oculography) 
  • Motion analysis (3-D infrared video system, Polhemus Motion Tracker)
  • Functional magnetic resonance imaging (fMRI)
Current Grants

Cooperation with

A. Berthoz (College de France, Paris, France)
J. Conradt (TU München)
J. Hermsdörfer (TU München) 
S.Hirche (TU München)
Y. Ivanenko (Santa Lucia Foundation, Rome)
A. Knoll (Robotics and Embedded Systems, TUM Munich)
S Marti, D. Straumann (Dept. of Neurology, Univ. Zurich, Switzerland)
T. Mergner (Dept. of Neurology, Univ. Freiburg, Germany) 
H. Mittelstaedt (MPIV Seewiesen, Germany)
L. Mujica-Parodi, (Stony Brook, NY, USA)
M. Mustari (University of Washington, Seattle, USA)
B. Seemungal, A. Bronstein (Imperial College, London)
Zhuanghua Shi (Dept. of Psychology, LMU Munich) 
H. Straka (Neurobiologie LMU)